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Updated: Sep 9, 2025

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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高齢者の脳縮,認知機能低下,認知症のリスクとの血性有機汚染物質の関連性

Sophie Lefèvre-Arbogast1, Pierre Scala2, Aurore Zorilla2

  • 1Univ. Bordeaux, Inserm, BPH, U1219, F-33000 Bordeaux, France; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, F-35000 Rennes, France.

Environment international
|September 3, 2025
PubMed
まとめ

耐久性有機汚染物質 (POP) は高齢者の認知症リスクと関連していません. しかし,特定のPOPはAPOE遺伝子型によって異なった効果を示し,APOE-ɛ4キャリアにおいて有害な関連性を示した.

キーワード:
アルツハイマー病コホート研究認知症オルガノクロリン化合物持続的な有機汚染物質ポリ塩化ビフェニル

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