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Updated: Sep 9, 2025

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells
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EGFR/VEGFR-2の阻害剤としてのベンジミダゾール基ハイブリッドとその他の酵素との組み合わせ:設計,合成,および活性

Anelia Mavrova1, Denitsa Yancheva2

  • 1University of Chemical Technology and Metallurgy, 8 Kliment Ohridski Blvd., 1756 Sofia, Bulgaria.

Bioorganic chemistry
|September 3, 2025
PubMed
まとめ

ベンジミダゾールのハイブリッドは,EGFRとVEGFR-2の強力な阻害を示しています. これらの化合物は 血管新生抑制特性と 二重抑制効果を示し 新しいがん治療法への道を切り開いています

キーワード:
ベンジミダゾールハイブリッド細胞毒性EGFR合成VEGFR阻害剤

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