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Updated: May 5, 2026

Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
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Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity

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クラード2.3.4.4のH5Nxインフルエンザウイルスを標的としたHADNAワクチンは,マウスとフレットにおける幅広いクロスクラード保護を提供します

Chang-Ung Kim1, Won-Suk Choi2, Pureum Lee3

  • 1Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea; College of Pharmacy, Chosun University, Gwangju, South Korea.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|September 3, 2025
PubMed
まとめ

鳥インフルエンザのH5Nxウイルスを標的とした新しいDNAワクチンは有望である. 強力な免疫反応を誘発し,動物モデルにおける複数のH5Nxクラードに対する広範な保護を提供し,潜在的なパンデミック防御を提供します.

キーワード:
CD8+ T細胞クラード2.3.4.4クロス・プロテクティブ・イムニティDNAワクチンH5Nx ウイルスヘモグルチニン高病原性鳥インフルエンザ (HPAI)

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