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Updated: Sep 9, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

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自己免疫疾患における標的型タンパク質分解:メカニズムから治療の突破

Yuxin Song1, Boyang Zhou1, Jiangang Long1

  • 1Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, China.

Journal of autoimmunity
|September 3, 2025
PubMed
まとめ

標的型タンパク質分解 (TPD) 技術は,自己免疫疾患で病気を引き起こすタンパク質を排除するための正確な方法を提供します. PROTACを含むこれらの先進的な方法は,現在の薬の限界を克服することによって,より効果的で個別化された治療の約束を示しています.

キーワード:
自己免疫疾患LYTAC についてMGD についてプロタック標的型タンパク質の分解

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