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Updated: Sep 9, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
07:08

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

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ビスフェノールAとDi-n-ブチルフタレットは,CD36媒介のBMSCの自己死抑制とエクソソーム誘発の骨格形成を介して双方向的に骨の恒常性を破壊する

Wenhao Wang1, Anquan Ma1, Chuanyao Zhai1

  • 1School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250000, China.

Journal of hazardous materials
|September 3, 2025
PubMed
まとめ

ビスフェノールA (BPA) とディンブチルフタラート (DBP) は幹細胞のCD36を標的とし,骨の形成を阻害し,骨の分解を促進します. 動物モデルでのCD36を静止すると,骨の修復が回復し,治療目標としてCD36が示唆された.

キーワード:
オートファジービスフェノールA骨の恒常性CD36 についてディ-n-ブチルフタレットエクソソーム

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