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Updated: Sep 9, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

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DDRキナーゼの阻害は,カスパース3の活性化によって,タクソールに対する過敏症を引き起こす

Megan Zaiger1, Junko Maeda1, Mami Murakami2

  • 1Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.

Biochemical and biophysical research communications
|September 3, 2025
PubMed
まとめ

DNAダメージ応答 (DDR) キナーゼを阻害すると,がん細胞死が増加し,Taxol化学療法が強化されます. ATM,ATR,DNA-PKをターゲットにしたこのアプローチは,Taxolの

キーワード:
ATM についてATR についてカスパース-3DNA-PK についてタクソール

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