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Updated: Sep 9, 2025

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Published on: June 2, 2023

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リンバチニブとセトキシマブの1期1b試験

Lara A Dunn1, Alan L Ho1, Loren S Michel1

  • 1Head and Neck Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Oral oncology
|September 3, 2025
PubMed
まとめ

レンバチニブとセトキシマブの組み合わせは,再発性/転移性頭頸部状細胞癌 (HNSCC) の治療に有望な効果を示しています. この研究では,HNSCC患者で顕著な客観的応答率 (ORR) を有する最大許容量 (MTD) が特定されました.

キーワード:
セトゥキシマブエピデルマ・成長因子受容体レセプタータンパク質チロシンキナーゼ阻害剤受容体,繊維細胞成長因子頭と首の状細胞がん

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