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Updated: Sep 9, 2025

Immunohistochemical Detection of 5-Methylcytosine and 5-Hydroxymethylcytosine in Developing and Postmitotic Mouse Retina
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卵細胞におけるCpG超メチル化の防止は,マウスの発達を保障する

Yumiko K Kawamura1, Evgeniy A Ozonov2, Panagiotis Papasaikas2

  • 1Friedrich Miescher Institute for Biomedical Research, 4056 Basel, Switzerland.

Developmental cell
|September 3, 2025
PubMed
まとめ

ヒストン脱メチラゼKDM2AとKDM2Bは,卵細胞における異常なDNAメチレーションを防止する. この表遺伝的調節は遺伝子転写と早期の胚の発達に不可欠である.

キーワード:
CpG島DNAメチル化KDM2AKDM2B についてPRC1 (中国)ポリコンブ胚形成母性表遺伝子遺伝卵細胞再プログラム

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