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Updated: May 5, 2026

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
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Published on: May 21, 2010

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スピノセレベラアタキシア1型 (SCA1) のポンチン体積変化の予測有効性

Teije H van Prooije1, Kirsten C J Kapteijns1, Jack J A van Asten2

  • 1Department of Neurology, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center, the Netherlands.

Neurobiology of disease
|September 3, 2025
PubMed
まとめ

ポンチンの体積減少は,脊椎小脳性アタキア1型 (SCA1) の進行に対する敏感なマーカーである. 1年間のポンチン量の変化は,将来の臨床減少を予測し,SCA1臨床試験におけるその使用を支持する.

キーワード:
アタキシア神経イメージングSCA1 について試験準備

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