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Updated: Jun 15, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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肝臓代謝の存在におけるアンドロゲン反応の評価のための二室共同培養システムに対する科学的信頼の確立

Tessa C A van Tongeren1, Susan J Hall2, Samantha J Madnick3

  • 1Division of Toxicology, Wageningen University and Research, Wageningen 6700 EA, the Netherlands.

Toxicology letters
|September 3, 2025
PubMed
まとめ

この研究は,薬物の毒性を評価するための二室共同培養システムを検証しています. このシステムは,代謝に依存するアンドロゲン受容体の反応を正確に捕捉し,内分泌活動評価の信頼性を高めます.

キーワード:
3D HepaRG マイクロ組織AR-CALUXアール・インディゴ毒性試験インビトロ検査

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