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Updated: Sep 9, 2025

Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster
04:59

Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster

Published on: March 28, 2025

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核タンパク質DCAF13は,rDNA転写とリボソーム生殖を促進することによって,非小細胞肺がん細胞の増殖を促進する

Xiao-Min Wang1, Meng-Dan Lv1, Zhong-Jie Wu2

  • 1Department of Basic Medicine, College of Medicine, Jiaxing University, 118 Jiahang Road, Jiaxing 314001, Zhejiang, P. R. China.

The Journal of biological chemistry
|September 3, 2025
PubMed
まとめ

DDB1およびCUL4関連因子13 (DCAF13) は,リボソームRNA遺伝子 (rDNA) の転写を強化することによって,非小細胞肺がん (NSCLC) の成長を促進する. DCAF13またはrDNAの転写を阻害すると,NSCLC細胞の増殖が著しく減少し,DCAF13を治療目標として強調します.

キーワード:
DCAF13 についてがん生物学肺がん腫瘍遺伝子rDNA についてリボソーム生物生成転写規制について

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