関連する実験動画

Updated: Sep 9, 2025

Reconstitution of Msp1 Extraction Activity with Fully Purified Components
05:52

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Published on: August 10, 2021

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Get4/5の基板結合室の改造: GET経路による尾部固定タンパク質標的化に関する洞察

Diego Granados-Villanueva1, Andrew Rossow2, Kelly H Kim1

  • 1Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.

The Journal of biological chemistry
|September 3, 2025
PubMed
まとめ

Get4/5複合体は,Get3結合室を開き,Sgt2からテールアンカーされたタンパク質 (TA) の転送を容易にする. このガイドド エントリー (GET) 経路の構造的な洞察は,膜タンパク質をターゲットにするための新しいメカニズムを明らかにします.

キーワード:
GET パスウェイシェーパロンクリオ・エム膜タンパク質タンパク質複合体タンパク質ターゲティングタンパク質とタンパク質の相互作用尾を固定したタンパク質

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