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関連する概念動画

Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

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Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Breathing01:05

Breathing

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The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
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Alveoli and Alveolar Ducts01:26

Alveoli and Alveolar Ducts

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The respiratory zone of the human body, which stands in contrast to the conducting zone, comprises the structures that actively participate in the exchange of gases. The initiation of this zone is marked by the terminal bronchioles converging into respiratory bronchioles, the tiniest bronchiole classification. The respiratory bronchioles give way to the alveolar ducts that opens into a congregation of alveoli. Actively involved in gas exchange, alveoli resemble tiny sacs similar to clusters of...
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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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関連する実験動画

Updated: Sep 9, 2025

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
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Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

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大気汚染と胞の健康

Carmelo Sofia1,2, James G H Parkin1, Joseph A Bell1,3,4

  • 1School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.

European respiratory review : an official journal of the European Respiratory Society
|September 3, 2025
PubMed
まとめ
この要約は機械生成です。

大気汚染は肺膜に害を及ぼし 肺間疾患のリスクを高めます これらの影響を理解することは 脆弱な集団の呼吸器疾患を予防するために不可欠です

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In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
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Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
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Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

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関連する実験動画

Last Updated: Sep 9, 2025

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
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Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

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In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
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科学分野:

  • 環境 健康
  • 肺科
  • 毒理学について

背景:

  • 大気汚染は 世界中で何百万もの早期死亡を引き起こし 主に呼吸器系に影響します
  • 呼吸道疾患や肺がんに影響を及ぼすことは知られていますが,肺膜と肺間膜への影響はあまり知られていません.
  • 空気汚染が 肺間異常や繊維性肺間疾患と 結びついていることが 明らかになっています

研究 の 目的:

  • 大気汚染が胞の健康に及ぼす影響に関する疫学的な証拠をレビューする.
  • 大気汚染の成分,粒子の大きさ,個々の感受性が 胞にどのように影響するか調べる.
  • 病原性メカニズムと 肺間疾患の進行に関する知識のギャップについて議論する.

主な方法:

  • 大気汚染と胞の健康に関する疫学研究のレビュー
  • 空気汚染の成分,粒子の大きさ,および感受性の要因の分析
  • 病原性メカニズムと現在の知識のギャップの議論

主要な成果:

  • 大気汚染の曝露は 肺膜損傷と 肺間異常と関連しています
  • 粒子の大きさは膜の浸透と潜在的損傷に影響する.
  • 個人の感受性は,大気汚染の暴露に対する反応を調節する可能性があります.

結論:

  • 大気汚染は肺膜の健康を著しく害し 肺間プロセスに寄与します
  • 病原性メカニズムを明らかにし,リスクのある個人を特定するには,さらなる研究が必要です.
  • 脆弱な集団を対象とした介入は,大気汚染に関連する肺疾患を予防することができます.