スペインにおける脳卒中死亡率の傾向を理解する: 年齢・期間・コホートと結合点に関する包括的な分析
L Cayuela1, E Zapata-Arriaza2, A de Albóniga-Chindurza2
1Department of Internal Medicine, Hospital Severo Ochoa, Leganés, Spain.
Neurologia
|September 3, 2025
まとめ
スペインの脳卒中死亡率は1982年から2021年の間に期間とコホート効果により減少した. しかし,最近の傾向は,脳卒中予防戦略の継続の必要性を強調しています.
科学分野:
- 流行病学
- 公衆衛生
- ゲロントロジー
背景:
- 1982年から2021年のスペインにおける脳卒中の死亡率の動向
- 脳卒中の死亡率に対する年齢期間コホート (A-P-C) 効果の分析
研究 の 目的:
- スペインの脳卒中死亡率に対するAPC効果を更新し評価する.
- 脳卒中の死亡率の傾向と要因を特定する.
主な方法:
- 脳卒中の死亡率と人口統計に関する国家統計局のデータ (1982-2021) を利用した.
- 率の推定とトレンド分析のためのJoinpointのトレンド分析ソフトウェアを使用しています.
- A-P-C効果を推定するために,確率のペナルティ関数を持つログ・リニア・ポアソンモデルを適用した.
主要な成果:
- 年齢で標準化された脳卒中死亡率は男女ともに減少した (男性4.3%,女性4.6%).
- 30歳から64歳までの女性の割合は 2012年以降安定しています
- 出産コホートは相対リスクの低下傾向を示していますが,この減少は1947年から1962年に生まれた女性の場合は減速し,過去10年間で男女ともに安定/減速しました.
結論:
- 期間とコホート効果はスペインの脳卒中死亡率の減少に大きく影響した.
- 死亡率の減少は,若いコホートにおける発生率の潜在的な増加を相殺せず,減速した/停滞した減少につながります.
- 継続的に脳卒中予防に注力することは,現在の傾向を考慮して極めて重要です.
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