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Updated: Sep 9, 2025

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes
11:01

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes

Published on: August 24, 2021

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ハイアルーロナンの作用によるグリコカリクスの低下 がん細胞のマクロピノサイトーシスをp21のアップレギュレーションによって抑制する

Guangxin Luan1,2, Qian Guo1, Yiwen Liu1

  • 1Department of Molecular Biology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.

Biomacromolecules
|September 3, 2025
PubMed
まとめ

ハイアルロナンの関連グラコカリックス (HA-GCX) の厚さは,がん細胞のマクロピノサイトーシス (MP) と正の相関関係にある. HA-GCXを阻害すると,MPと癌細胞の増殖を抑制し,新たな治療目標を示唆する.

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