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Updated: Sep 9, 2025

06:46
Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
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消化管カンジダシスと逆流性消化管炎の発生との間の否定的な関連
Kyoichi Adachi1, Eiko Okimoto1, Utae Sakamoto1
1Health Center, Shimane Environment and Health Public Corporation, Japan.
Internal medicine (Tokyo, Japan)
|September 3, 2025
まとめ
リフルス食道炎 (RE) は,食道内酸性による食道カンジダ症から保護する. しかし,食道内の異形性胃粘膜 (HGM) は,この研究で同様の保護的関連性を示しませんでした.
科学分野:
- 胃腸内科
- 感染症
- 腫瘍学
背景:
- 逆流性食道炎 (RE) は,胃食道酸逆流によるものです.
- 子宮頸部の胃粘膜 (HGM) は酸を分泌することができる.
- 食道内酸性の食道内カンジダ症に対する保護的役割は調査中です.
研究 の 目的:
- REまたはHGMによる食道内酸性状態が食道 кандидозを予防するかどうかを判断する.
- 食道 кандидозの危険因子を特定するために.
主な方法:
- 5,221人の成人を対象に,食道胃腸内視鏡検査 (EGD) を実施した.
- エンドスコピーで食道 кандидоз,RE,HGMを評価した.
- リスク要因を特定するために多重ロジスティック回帰分析を使用しました.
主要な成果:
- 食道カンジダシス,RE,HGMはそれぞれ3. 4%,21. 4%,7. 0%の患者で発見されました.
- 高齢,アルコールの摂取,および併発性疾患は,カンジダ症の重要な危険因子でした.
- REは食道 кандидозとの負の相関を示したが,HGMはそうではなかった.
結論:
- REは食道カンジダ症とネガティブに相関しており,保護効果を示唆しています.
- 子宮頸管のHGMは食道 кандидозの発生と有意に関連しませんでした.
- 併発症や生活習慣の要因は 食道カンジダ症の主要な危険因子です
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