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Updated: Sep 9, 2025

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer
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腫瘍の微小環境における免疫抑制メカニズムの観点から,進行した胃がん患者の組み合わせ免疫療法の開発

Kosaku Mimura1,2, Koji Kono1

  • 1Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine.

Fukushima journal of medical science
|September 3, 2025
PubMed
まとめ

プログラムされた細胞死1 (PD-1) 抗モノクローナル抗体 (mAbs) を併用した組み合わせ免疫療法は,進行した胃がん (GC) に対して有望である. このアプローチは,腫瘍の微小環境における免疫抑制メカニズムをターゲットにすることで,抵抗を克服することを目的としています.

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