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Updated: Sep 9, 2025

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

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ステチン不耐症の患者にとって最適な非ステチン脂質低下療法を選択する: 系統的レビューとネットワークメタ解析

Wattakorn Laohapiboolrattana1, Paisit Kosum2, Mantiwee Nimworapan3

  • 1Division of Neurology, Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand (Dr. Laohapiboolrattana and Roongpiboonsopit).

Journal of clinical lipidology
|September 3, 2025
PubMed
まとめ

スタチンに不耐性のある患者では,エヴォロキュマブとエゼチミブを併用することで,最も効果的なLDL- Cの低下がもたらされます. この組み合わせは,他の非スタチンの治療法と比較可能な安全性プロファイルを示し,心臓血管リスク管理の実行可能な代替手段を提供します.

キーワード:
ベンペド酸エゼチミブPCSK9阻害剤スタチンの不耐性

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