関連する実験動画

Updated: Sep 9, 2025

2 in 1: One-step Affinity Purification for the Parallel Analysis of Protein-Protein and Protein-Metabolite Complexes
08:23

2 in 1: One-step Affinity Purification for the Parallel Analysis of Protein-Protein and Protein-Metabolite Complexes

Published on: August 6, 2018

11.5K

保存されたインターフェースは,プロカリオットメタボロンにおける複数のタンパク質相互作用を媒介する

Sanchari Bhattacharyya1,2, Srivastav Ranganathan3,4, Sourav Chowdhury3,5

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA. bhattacharyya.sanchari@gmail.com.

Molecular systems biology
|September 3, 2025
PubMed
まとめ

研究者はE. coliの代謝における1225のタンパク質相互作用 (PPI) をマッピングし,代謝経路を加速する酵素群を明らかにした. この研究は,メタボロン生体物理学と一時的な酵素複合体の構造を明らかにする.

キーワード:
アルファフォールド酵素フックスメタボロンスプリット YFP暫定的なPPI

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