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Updated: Sep 9, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

Published on: January 7, 2019

8.4K

癌におけるTRIB3-MYC軸をターゲットにする:メカニズム的洞察と治療的破壊戦略

Emadeldin M Kamel1, Sulaiman A Alsalamah2, Ahmed A Allam2

  • 1Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62514, Egypt.

Investigational new drugs
|September 3, 2025
PubMed
まとめ

トリブルズ偽キナーゼ3 (TRIB3) は,MYCを結合する新しい標的であり,主要ながん誘発因子です. TRIB3を抑制すると,MYCのレベルが効果的に低下し,様々ながんの腫瘍の成長を抑制し,新しい治療法を提供します.

キーワード:
ガン治療MYC についてタンパク質とタンパク質の相互作用トリブ3ウビキチネーション

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Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

Published on: August 25, 2021

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Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays07:42

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays

Published on: September 19, 2018

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