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Updated: Sep 9, 2025

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
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ウイルス学的に抑制されたHIV感染に対するドゥルテグラビール,アバカビール,ラミブジンの継続治療と比較して,体重,体質または代謝パラメータの変化はありません (AVERTAS試験)

Karen Brorup Heje1, Magnus Søltoft Lindhardt1, Alessandra Meddis2

  • 1Department of Infectious Diseases, Center of Clinical Research and Disruption of Infectious Diseases (CREDID), Copenhagen University Hospital - Amager and Hvidovre, Kettegaard Allé 30, Hvidovre, 2650, Denmark.

BMC infectious diseases
|September 3, 2025
PubMed
まとめ

HIV感染者におけるアバカビール (ABC) 投与の中止は,体重増加や代謝の健康を48週間にわたって有意に変化させなかった. ABCの継続と停止は,同様の軽度の体重増加と関連していました.

キーワード:
アバカビール抗レトロウイルス療法,高度な活性体重HIV ウイルス体重増加

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