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Updated: Sep 9, 2025

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

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TLQP-21ペプチドから派生した新しい補足3a受容体アゴニストとアンタゴニストのクラス

Pedro Rodriguez1, Jean Pierre Pallais1, Rongjun He2

  • 1Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.

Journal of medicinal chemistry
|September 3, 2025
PubMed
まとめ

研究者は新しいペプチド類を作ることで,補足3a受容体 (C3aR) を最適化しました. これらの改変はC3aRのシグナル選択性と効力を高め,炎症性,代謝性,および神経疾患に対する新しい治療方法を提供します.

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