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Updated: Sep 9, 2025

Differentiated Mouse Adipocytes in Primary Culture: A Model of Insulin Resistance
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肝臓GR/miR-1224プログラムによる子宮内成長制限によるインスリン抵抗性のメカニズムと病理学的重要性

Yongguo Dai1,2, Xiaoling Guo1, Pengxia Yu1

  • 1Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|September 3, 2025
PubMed
まとめ

ネズミのモデルでの産前カフェイン暴露は,初期インスリン感受性につながる子宮内成長制限 (IUGR) を引き起こしますが,後にプログラムされた肝臓信号を通してインスリン抵抗性 (IR) が発現します.

キーワード:
高度グリケーションの最終製品グルココルチコイドインスリン抵抗性miR‐1224 について産前カフェインへの曝露

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