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Updated: Sep 9, 2025

Subcellular Fractionation for ERK Activation Upon Mitochondrial-derived Peptide Treatment
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多種哺乳類のサイトカインとエリトポエチン模倣ペプチドは,植物遺伝的に保存されたサイトカイン受容体のような因子3 (CRLF3) を介して昆虫のニューロンを保護する

Nina Hahn1, Debbra Y Knorr2, Björn Twellsieck3

  • 1Section of Translational Neuroimmunology, Department of Neurology and Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany.

Journal of neurochemistry
|September 4, 2025
PubMed
まとめ

ハエのサイトカイン受容体のような因子3 (CRLF3) は神経細胞をアポトーシスから保護する. この受容体はエリトポエチン (Epo),EV-3,および短いペプチドに結合し,CRLF3が脊椎動物のサイトカイン受容体の進化的前駆体であることを示唆しています.

キーワード:
サイトカイン受容体のような因子3 (CRLF3)エリトロポエチンエリトロポエチンミメティックペプチド進化についてヒトのサイトカイン神経保護

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