関連する実験動画

Updated: Sep 9, 2025

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
08:38

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

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ポサコナゾールとタクロリムスの相互作用に対する経路,濃度,遺伝的多型性の影響

Masatomo Kuno1, Yusuke Okayama1,2, Yukako Yasui3,4

  • 1Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

British journal of clinical pharmacology
|September 4, 2025
PubMed
まとめ

この研究では,ポサコナゾールはタクロリムスの濃度に有意な影響を及ぼし,投与量の調整が必要であることが判明しました. タクロリムスの経路,ポサコナゾールの濃度,遺伝的変異などの要因がこれらの薬物相互作用に影響します.

キーワード:
アロジェニックの血液形成細胞移植薬物相互作用遺伝子ポリモルフィズムポサコナゾールタクロリムス

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