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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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Taste Buds and Receptors01:20

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Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Updated: Sep 9, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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非セリアック性グルテン/小麦感受性の傾向:自己管理の問題?

F Manza1,2, S A Raju2,3, R M Harrop4

  • 1Department of Translational Medicine, University of Ferrara, Ferrara, Italy.

Scandinavian journal of gastroenterology
|September 4, 2025
PubMed
まとめ

グルテンフリー食品の販売が増加しているにも関わらず,グルテン/小麦感受性 (NCGWS) の患者では,グルテンフリー食品の摂取量が低い. 多くのNCGWS患者は,食事管理に伴う継続的な課題を示し,引き続き医師の助言を求めています.

キーワード:
非セリアック性グルテン感受性フォローアップグルテン過敏症グルテンフリーダイエットグルテンフリーダイエットグルテンフリー市場小麦の感受性

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科学分野:

  • 胃腸内科
  • ダイエット 科学
  • 公衆衛生

背景:

  • 非セリアック性グルテン/小麦過敏症 (NCGWS) は,セリアック病や小麦アレルギーのない個人に影響します.
  • グルテンフリーダイエット (GFD) は,NCGWSの主な管理戦略です.
  • 最近の傾向は,COVID-19の流行後のNCGWS診断の減少の可能性を示唆しています.

研究 の 目的:

  • グルテンフリー (GF) 製品の英国市場動向を分析する.
  • 自己報告されたNCGWSの患者における長期のGFDアデンス評価.
  • 認知されたGFDの有効性を評価し,NCGWS患者のさらなる医療アドバイスの必要性を評価する.

主な方法:

  • イギリスのGF製品販売データと買い物客の見解を分析した.
  • 2006年から2018年の間に診断されたNCGWS患者にはフォローアップアンケートが実施されました.
  • GFDアデレンスはBiagiスコアを使用して測定され,セリアック病 (CD) のコホートと比較されました.

主要な成果:

  • GF製品の売上高は2億1400万ポンド (2014年) から6億7000万ポンド (2024年) に大幅に増加した.
  • NCGWS患者はGF製品購入者の9.7%を占めた.
  • NCGWS患者は,CD患者と比較してGFDアデレンスが著しく低下した (p < 0. 05).
  • NCGWS患者の36%が退院後,さらに医師の助言を求めた.

結論:

  • 紹介の減少の可能性にもかかわらず,NCGWSのためにGFダイエットを使用する人の有意な割合があります.
  • NCGWS患者におけるGFDの長期的遵守は最適ではない.
  • NCGWSの管理における継続的な医療ニーズを理解するために,さらなる研究が必要になる可能性があります.