非セリアック性グルテン/小麦感受性の傾向:自己管理の問題?
F Manza1,2, S A Raju2,3, R M Harrop4
1Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Scandinavian journal of gastroenterology
|September 4, 2025
まとめ
グルテンフリー食品の販売が増加しているにも関わらず,グルテン/小麦感受性 (NCGWS) の患者では,グルテンフリー食品の摂取量が低い. 多くのNCGWS患者は,食事管理に伴う継続的な課題を示し,引き続き医師の助言を求めています.
科学分野:
- 胃腸内科
- ダイエット 科学
- 公衆衛生
背景:
- 非セリアック性グルテン/小麦過敏症 (NCGWS) は,セリアック病や小麦アレルギーのない個人に影響します.
- グルテンフリーダイエット (GFD) は,NCGWSの主な管理戦略です.
- 最近の傾向は,COVID-19の流行後のNCGWS診断の減少の可能性を示唆しています.
研究 の 目的:
- グルテンフリー (GF) 製品の英国市場動向を分析する.
- 自己報告されたNCGWSの患者における長期のGFDアデンス評価.
- 認知されたGFDの有効性を評価し,NCGWS患者のさらなる医療アドバイスの必要性を評価する.
主な方法:
- イギリスのGF製品販売データと買い物客の見解を分析した.
- 2006年から2018年の間に診断されたNCGWS患者にはフォローアップアンケートが実施されました.
- GFDアデレンスはBiagiスコアを使用して測定され,セリアック病 (CD) のコホートと比較されました.
主要な成果:
- GF製品の売上高は2億1400万ポンド (2014年) から6億7000万ポンド (2024年) に大幅に増加した.
- NCGWS患者はGF製品購入者の9.7%を占めた.
- NCGWS患者は,CD患者と比較してGFDアデレンスが著しく低下した (p < 0. 05).
- NCGWS患者の36%が退院後,さらに医師の助言を求めた.
結論:
- 紹介の減少の可能性にもかかわらず,NCGWSのためにGFダイエットを使用する人の有意な割合があります.
- NCGWS患者におけるGFDの長期的遵守は最適ではない.
- NCGWSの管理における継続的な医療ニーズを理解するために,さらなる研究が必要になる可能性があります.
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