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Updated: Sep 9, 2025

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
07:33

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

14.4K

低圧イオン化により,タンパク質とタンパク質複合体の原生質量スペクトロメトリが改善される

Jake P Violi1, Chong Zhang1, William A Donald1

  • 1School of Chemistry, UNSW Sydney, Sydney, NSW, 2052, Australia.

Angewandte Chemie (International ed. in English)
|September 4, 2025
PubMed
まとめ

低圧イオン化は,特に高塩溶液では,ネイティブ質量スペクトロメトリー (MS) の性能を大幅に向上させる. この方法は信号の強度とタンパク質の相互作用の検出限界を改善し,以前は困難な条件下で分析を可能にします.

キーワード:
イオン移動スペクトロメトリーネイティブ・マススペクトロメトリータンパク質複合体低圧イオン化トレースタンパク質の分析

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