関連する実験動画

Updated: Sep 9, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
11:53

Substrate Generation for Endonucleases of CRISPR/Cas Systems

Published on: September 8, 2012

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タイプIIIのCRISPR-Casロシにおけるリングヌクレアスの多様性と豊富さ

Ville Hoikkala1, Haotian Chi1, Sabine Grüschow1

  • 1School of Biology, University of St Andrews, St Andrews, UK.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
|September 4, 2025
PubMed
まとめ

タイプIIIのCRISPR-Casシステムは,ファグ防御のために循環性オリゴアデニラート (cOAs) を使用する. この研究は,COAを分解する新しい環核酸 (RNA) を確認し,細菌の免疫におけるこれらのシグナル伝達分子の広範な調節を明らかにした.

キーワード:
CRISPRについてサイクルヌクレオチドフォスフォディエステラーゼリングヌクレアゼ

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