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Updated: Sep 9, 2025

The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues
07:39

The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues

Published on: June 16, 2018

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[METTL3媒介によるm6Aメチル化改変による肺腺がんの侵入と転移の調節におけるpiR-hsa-26925のメカニズム]

Y Q Luo1, N Wang2, J P Li1

  • 1Department of Respiratory and Critical Care Medicine, Qilu Hospital of Shandong University, Ji'nan 250012, China.

Zhonghua yi xue za zhi
|September 4, 2025
PubMed
まとめ

PIWIと相互作用するRNA piR- hsa- 26925は,METTL3と相互作用し,EPHB2のm6Aメチル化を変化させ,細胞侵入を促進する.

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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