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Updated: Sep 9, 2025

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腸内微生物群のタンパク質BOC1は,骨髄系由来の抑制細胞の分化を抑制することによって,免疫チェックポイント阻害剤のような活性を示す

Laureen Bardouillet1, Maria Lucia Orsini Delgado1, Caroline Matondo1

  • 1Drug Discovery Department, Enterome, Paris, France.

Frontiers in immunology
|September 4, 2025
PubMed
まとめ

研究者はBOC1という腸内細菌のタンパク質を発見し CD200R1と相互作用し 癌に対する免疫反応を高めました このタンパク質は,免疫チェックポイント阻害剤 (ICI) に類似した新しい免疫療法として潜在性を示しています.

キーワード:
CD200R1 についてMDSC についてガンに対する免疫療法腸内微生物群免疫チェックポイント阻害剤

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