妊娠中の母親の喫煙が子供に及ぼす鬱や不安の行動:メタ分析
Kui Zhang1, Yu Wang2, Zhilong Shu1
1Department of Forensic Pathology, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, China.
Depression and anxiety
|September 4, 2025
まとめ
妊娠 中 の 母親 の 喫煙 は 子孫 の 増加 を もたらす
科学分野:
- 生後期の精神的健康
- 子孫の精神疾患
- 開発に対する環境の影響
背景:
- 妊娠中の母親の喫煙は,子孫の健康への悪影響の危険因子として知られています.
- 産前喫煙と子孫のうつ病や不安症との具体的な関連は まだ議論されている.
- これらのリスクを理解することは 公衆衛生の介入に不可欠です
研究 の 目的:
- 妊娠中の母親の喫煙と子孫のうつ病や不安症のリスクとの関連を体系的に評価する.
- メタアナリシスを用いてリスクを定量化します
- 喫煙量に基づいて用量反応の関係を探求する.
主な方法:
- PubMed,Web of Science,およびOVIDデータベースの体系的な文献検索 (2000〜2024年)
- 合計1,775,220人の参加者を含む研究11件.
- 確率比 (OR) と95%信頼区間 (CI) を用いたメタ分析で関連性を評価した.
主要な成果:
- 妊娠中の母親の喫煙は,子孫のうつ病のリスク増加と有意に関連していた (OR=1. 33,95%CI=1. 09-1.63).
- 妊産婦の重度の喫煙 (≥ 10 枚/日) は,子孫におけるうつ病 (OR = 1.61, 95% CI = 1. 21~2.14) と不安症 (OR = 1.51, 95% CI = 1. 32~1. 72) のリスクをさらに高めました.
- より高い喫煙レベルはより大きなリスクと相関しています.
結論:
- 妊娠中の母親の喫煙は 子孫にうつ病や不安のリスクを高めます
- 妊娠中に喫煙が増加すると リスクが高まります
- 母親の喫煙を防止し,産前喫煙を減らすことは,子孫の精神的健康を改善するために不可欠です.
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