口腔溶解フィルムの口腔病原菌と口腔病原菌に対する短期的影響:非ランダム化試験
Mu-Yeol Cho1, Je-Hyun Eom1, Eun-Mi Choi1
1Apple Tree Institute of Biomedical Science, Apple Tree Medical Foundation, Goyang-si, Republic of Korea.
Frontiers in microbiology
|September 4, 2025
まとめ
口内溶解フィルム (ODF) は,悪口の化合物と有害な細菌を大幅に減少させました. この便利なアプローチは口臭を抑え 虫歯を予防するのに役立ち 舌の掃除の代替品となります
科学分野:
- 口腔 衛生
- 微生物学
- 生物化学
背景:
- ハリトーシスは 社会的交流や生活の質に 大きく影響します
- 口臭と関連する口腔細菌の管理は 口腔衛生に不可欠です
研究 の 目的:
- 口内溶解フィルム (ODF) が口臭や口内病原菌を減らす効果を評価する.
- ODFと口臭管理のための舌掃除剤を比較する.
主な方法:
- ODFの摂取量 (n=15) と口臭のある成人における7日間の舌の浄化 (n=15) を比較した試験試験が行われました.
- 測定には,口臭分析器による揮発性硫黄化合物 (VSC) とqPCRによる口腔細菌が含まれていた.
- 参加者は口臭と診断された成人でした.
主要な成果:
- ODFは水素 (H2) を55. 1%,メチルメルキャプタン (CH3SH) を54. 4% (p < 0. 05) 減少させた.
- ODFはまた,Streptococcus mutansを27. 9%減少させた (p = 0. 022).
- トレポネマ・フォースチアがわずかに増加した.
結論:
- ODFは,重要な口臭化合物を効果的に減らし,カリオゲン菌に対して抗菌効果を発揮する.
- ODFは,口臭の管理と潜在的な虫歯の予防のための便利な代替案です.
- これらの発見を検証するために,さらなる大規模なランダム化試験が推奨されます.
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