食中の微生物と機能的消化不良:治療上の利益のために腸内微生物を調節する
Qi Huang1, Fei You1, Fengxia Liang2
1Department of Rehabilitation, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Frontiers in nutrition
|September 4, 2025
まとめ
食中の微生物は,腸の健康を改善することで,機能性消化不全 (FD) を治療することができます. このレビューでは,これらの微生物がどのように作用し,FDのパーソナライズされた治療戦略について議論します.
科学分野:
- 胃腸内科
- 微生物学
- 栄養学
背景:
- 機能性消化不良 (FD) の病原性は腸内微生物学的不均衡と関連している.
- 食中の微生物は,腸内微生物群を調節することで,FDの潜在的な治療方法を提供します.
- FDにおける微生物療法のためのメカニズムと最適なプロトコルについては,さらなる明確化が必要である.
研究 の 目的:
- FDの腸内微生物学的変化を体系的に検討する.
- 食中の微生物がFDを軽減する役割とメカニズムを批判的に検討する.
- 新しい診断技術を統合したFDのパーソナライズされた管理戦略について議論する.
主な方法:
- FD,腸内微生物群,および食事介入に関する研究の体系的な文献レビュー.
- マイクロエコロジーに関連するFDの提案された病原性メカニズムの分析.
- FDにおける微生物療法に関する臨床証拠の評価
主要な成果:
- FDは腸内微生物学的不均衡の特定のパターンで特徴付けられています.
- 食中の微生物は,免疫調節と腸のバリア機能を含む様々なメカニズムを通じて,FDの症状に影響を与えることができます.
- 新興の診断ツールによって 微生物治療の個別化が 可能になるかもしれません
結論:
- 食中の微生物は,微生物学的規制によるFD管理の有望な戦略です.
- 正確なメカニズムを明らかにし,治療プロトコルを最適化するためにさらなる研究が必要です.
- パーソナライズされた介入はFDの治療結果を改善する可能性を秘めています.
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