喉のクリア・セル癌: 体系的なレビュー

Gabriele Noreikaite¹, Savannah Nicks¹, Daniel Lofgren²

¹Department of Otolaryngology-Head & Neck Surgery McLaren Oakland Hospital Pontiac Michigan USA.

OTO open

|September 4, 2025

まとめ

喉の透明細胞癌 (LCCC) は珍しい癌である. このレビューでは,LCCCはしばしば生存率の低い状態で,よりよい理解と治療戦略の必要性を強調しています.

科学分野:

腫瘍学
頭と首の手術
病理学について

背景:

喉のクリア細胞癌 (LCCC) は極めてまれな悪性腫瘍である.
既存の文献は,主に孤立した症例報告に限られている.
LCCCの包括的な特徴と傾向分析は欠けている.

研究の目的:

LCCCに関する既存の文献を体系的にレビューし,分析する.
LCCCの典型的な表現,治療方法,生存結果を特徴づける.
この珍しい喉腫瘍の潜在的傾向を特定するためです

主な方法:

PubMed,MedLine,そしてEmbaseのデータベースの体系的な文献検索.
1976年から2024年までの間,病理的に診断されたLCCCを報告した研究を含む.
7つの研究で9つの症例でPRISMAのガイドラインに従うデータ抽出.

主要な成果:

影響を受けた患者の大半は男性 (77. 7%) で,平均年齢は56. 5歳でした.
最も一般的な部位は頭部 (66. 6%) であり,しばしば先進的な局域疾患を示した.
主な治療法は手術 (66. 6%),再発率は高 (55. 5%) で,平均生存期間は低かった (9. 3ヶ月).

結論:

LCCCは稀で攻撃的な喉腫瘍で,しばしば頭蓋骨が転移する.
手術や化学放射線治療など治療方法は様々ですが生存率は低いままです
LCCC患者の治療結果を改善するためにさらなる研究が必要である.

キーワード:

頭頸部がん喉頭がん喉の透明細胞がん喉の非状細胞癌

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