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Updated: Sep 9, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
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Published on: January 7, 2019

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バイオインフォマティクス分析により,TCP1とNOTCH1は,胆管がんにおける5-フッ素ウラシル耐性を克服する潜在的な標的分子として特定された

Sonexai Kidoikhammouan1, Nopkamol Kanchanangkul2, Worachart Lert-Itthiporn2

  • 1Biomedical Sciences Program, Graduate School, Khon Kaen University, Thailand.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University
|September 4, 2025
PubMed
まとめ

この研究では,NOTCH1とTCP1が5 - フッ素ウラシル (5- FU) 耐性に関連した重要な遺伝子として,胆管がん (CCA) で特定されました. これらの発見は,CCA患者における5- FU化学療法の有効性を改善する潜在的な標的としてNOTCH1とTCP1を示唆しています.

キーワード:
5-フッ素ウラシルNOTCH1 についてTCP1 についてコランジオカルシノーマレジスタンス

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