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Updated: Sep 9, 2025

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Published on: June 2, 2022

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NAMPTは慢性腎臓病における血管カルシフィケーションの新薬である

Qianqian Dong1,2, Lihe Lu3, Xiuli Zhang1,2

  • 1Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, China. (Q.D., X.Z., L.F., A.C., Z.L., Y.Y., J.Z., X.L., Y.L., J.Y.).

Arteriosclerosis, thrombosis, and vascular biology
|September 4, 2025
PubMed
まとめ

ニコチナミド・フォスフォリボシルトランスフェラーゼ (NAMPT) は,SIRT1媒介のNotch信号を調節することによって,慢性腎臓疾患における血管結晶を抑制する. この発見は 心血管疾患の新たな治療目標となるのです

キーワード:
筋細胞,滑らかな筋肉ニコチナミド・フォスフォリボシルトランスフェラーゼ腎不全,慢性sirturn-1 (サーターン-1)血管のカルシフィケーション

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