関連する実験動画

Updated: May 2, 2026

Optimization and Utilization of Agrobacterium-mediated Transient Protein Production in Nicotiana
23:21

Optimization and Utilization of Agrobacterium-mediated Transient Protein Production in Nicotiana

Published on: April 19, 2014

41.7K

CRISPR/Cas9媒介によるALG3とGNTIのノックアウトと医薬品生産への応用

Dolgormaa Bataa1,2,3, Hiroyuki Kajiura1,4, Reimi Lai Sang Sawada-Choi1,2

  • 1International Center for Biotechnology, University of Osaka, Osaka, Japan.

Plant biotechnology journal
|September 4, 2025
PubMed
まとめ

ニコチア・ベンタミアナのN-グリコエンジニアリングは,CRISPR/Cas9編集を用いて,均一なトリマノシドのN-グリカンを生成した. この進歩により,植物特有のエピトープを除去することで,より安全で効果的なバイオ医薬品の生産が可能になります.

キーワード:
ニコシアナ・ベンタミアナCRISPR/Cas9についてN-アセチルグルコサミニルトランスフェラーゼIN-グリコエンジニアリングα1,3-マノシルトランスフェラーゼ

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Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio11:27

Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio

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Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System06:13

Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System

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関連する概念動画

CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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Transgenic Plants02:50

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
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CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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