肺転移患者における血清ビタミンD濃度
Tomas Hanslik1,2, Thomas Klikovits3,4, Vladimir Soska1,5
1Faculty of Medicine, Masaryk University, Brno, Czech Republic.
まとめ
多発性悪性腫瘍の患者は冬にビタミンD3濃度が低い. より大きな臨床試験が実施されるまで,特に冬の間,これらの患者に補給が有益である可能性があります.
科学分野:
- 腫瘍学
- 内分泌学
- 栄養学
背景:
- ビタミンD欠乏は,がんのリスクと死亡率の上昇と関連しています.
- ビタミンDのサプリメントが 癌患者のアウトカムに与える影響は不明です
研究 の 目的:
- 悪性腫瘍と肺転移歴のある患者の血清ビタミンD3レベルを評価する.
- 癌患者のビタミンD3濃度と臨床的要因の相関性を調べる
主な方法:
- 血清のビタミンD2およびD3濃度は,高性能液体染色体検査 (HPLC) を使用して測定されました.
- 38人の患者を分析した.
- データは季節,転移数,悪性病歴,ASA状態と相関した.
主要な成果:
- 血清のビタミンD3濃度は冬と比較して夏に著しく高かった.
- 肺に転移した患者と転移していない患者の間で,ビタミンD3濃度の有意な差は認められなかった.
- 冬には"つの悪性腫瘍を持つ患者は複数の悪性腫瘍を持つ患者よりもビタミンD3濃度が高い.
結論:
- ビタミンDのサプリメントは,特に冬に,多発性悪性腫瘍の患者にとって有益である可能性があります.
- これらの発見を確認し,勧告を導くために,より大きなコホートでのさらなる臨床試験が必要である.
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