関連する実験動画

Updated: Sep 9, 2025

Detection of RNA-binding Proteins by In Vitro RNA Pull-down in Adipocyte Culture
10:34

Detection of RNA-binding Proteins by In Vitro RNA Pull-down in Adipocyte Culture

Published on: July 22, 2016

23.8K

核酸とタンパク質によるRループの調節

Yiyun Zhang1, Xiaoyun Zheng1, Sumin Ye1

  • 1Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang Province 310058, China.

Essays in biochemistry
|September 4, 2025
PubMed
まとめ

Rループは細胞にとって不可欠ですが,バランスがとれなければゲノムの整合性を損なう可能性があります. この研究では,m6AとSUMOylationのようなRNAとタンパク質の改変がR-ループホメオスタシスを調節し,ゲノム安定性と遺伝子発現に影響を及ぼすことを調査しています.

キーワード:
DNA 損傷Rループゲノムの整体性翻訳後の修正ユビキチン

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iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution10:45

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