胎児における孤立した狭い空洞セプトム・ペルシドム:正常な発達の変異
Yihong Yang1, Shan Zhu1, Xin Yang1
1Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
まとめ
狭い穴隔膜 (CSP) を有する胎児は,通常,正常な体 callosum と良い神経発達の結果を持っています. この発見は,孤立した狭いCSPがしばしば正常な変異であることを示唆しています.
科学分野:
- 産前診断
- 胎児イメージング
- 神経発達小児科
背景:
- 洞穴隔膜 (CSP) は胎児の脳内の中線構造である.
- 3mm未満の狭いCSPは,産前超音波で特定することができます.
- 孤立した狭いCSPの影響を理解することは 正確な産前カウンセリングに不可欠です
研究 の 目的:
- 孤立した狭いCSPと診断された胎児の神経発達の結果を評価する.
- 単離された狭いCSPと体カロスの発達との関連を評価する.
- 孤立した狭いCSPが正常な変化を表すかどうかを判断する.
主な方法:
- 超音波で特定されたCSP異常の胎児症例の遡及的レビュー.
- 含有基準:隔離された狭いCSP (<3mm) が妊娠2期または3期に検出されました.
- MRI 検査結果,産前検査結果,産後神経発達評価との相関性
主要な成果:
- 孤立した狭いCSPを持つ79人の胎児が特定されました.
- MRIは94. 4%の症例で正常な肉体が示され,5. 6%の症例で部分的な発作が示された.
- すべての可用の神経発達のアウトカム (n=24) は,平均年齢31. 6ヶ月で正常であった.
結論:
- 胎児の孤立した狭いCSPは,通常,正常な体 callosumと関連しています.
- 孤立した狭いCSPを持つ胎児の神経発達の予後は一般的に好ましい.
- 孤立した狭いCSPは正常な胎児発達の変種と考えられます.
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