関連する実験動画

Updated: Sep 9, 2025

A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization
08:20

A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization

Published on: September 2, 2021

4.2K

CRISPR/Cas活動のプログラム可能な制御のためのトポロジー・エンジニアリングされたガイドRNA

Liang Cheng1,2

  • 1Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Laboratory of Molecular Recognition and Function, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.

Angewandte Chemie (International ed. in English)
|September 4, 2025
PubMed
まとめ

トポロジー・エンジニアリングされたガイドRNA (TE-gRNA) は,CRISPR遺伝子編集を精密に制御します. これらの高度なRNA構造は,条件付きおよび可逆の編集を可能にし,強化されたアプリケーションのための伝統的な方法の限界を克服します.

キーワード:
CRISPR/Casシステムゲノム編集制御ガイドRNAエンジニアリングRNA トポロジートポロジ・エンジニアリングによるガイドRNA

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