イタリアで2024年に慢性B型肝炎とデルタウイルスと診断された患者数:国家実世界データベースからの推定
Alessandro Loglio1, Ivan Gardini2, Massimiliano Conforti2
1Gastroenterology, Hepatology and Transplantation Division, ASST Papa Giovanni XXIII, Bergamo, Italy.
まとめ
更新されたデータは,イタリアで推定111,960人の慢性B型肝炎 (CHB) と9,360人の慢性デルタ型肝炎 (CHD) の患者を明らかにしています. この研究は,公衆衛生政策にとって重要な疫学的な洞察を提供します.
科学分野:
- ヘパトロジー
- 感染症
- 流行病学
背景:
- イタリアでは,B型肝炎ウイルス (HBV) とデルタ型肝炎ウイルス (HDV) の感染が著しく増加しています.
- 現在,慢性B型肝炎 (CHB) と慢性デルタ型肝炎 (CHD) の信頼性の高い最新の流行データはありません.
研究 の 目的:
- リアルなデータを用いて,イタリアにおけるCHBとCHDの現在の流行病学を決定する.
- 2024年のイタリアの成人集団におけるCHBとCHDの流行を推定する.
主な方法:
- CHBとCHDのための21の地域保健当局からの医療費免除データを使用しました.
- 30の胃腸内科,肝臓病科,感染症科で調査を行い,免除の報告不足を評価した.
主要な成果:
- 成人集団では推定111, 960例のCHB (0. 22%の罹患率) と9, 360例のCHD (0. 019%の罹患率) であった.
- CHBの60.3%とCHDの55.7%だけが特定のヘルスケア免除を受けていることが判明しました.
- 研究したコホートでは,抗HDVの流行率が7. 7%と報告された.
結論:
- この研究は,イタリアの成人のCHBとCHD患者数の堅実な見積もりを提供します.
- この発見は,ウイルス性肝炎の管理に関する公衆衛生政策決定の基礎となる.
関連する概念動画
Diseases of the Liver and Gallbladder
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Infectious Diseases and Their Occurrence
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Hepatitis
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction
Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...


