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Updated: Sep 9, 2025

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
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免疫および成長因子シグナル伝達経路は,乳がん患者の抗タイプI型インスリン型の成長因子受容体療法に対する病理学的完全反応と関連している

Emmanuel F Petricoin1, Denise M Wolf2, Christina Yau3

  • 1Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia.

Clinical cancer research : an official journal of the American Association for Cancer Research
|September 4, 2025
PubMed
まとめ

乳がんにおけるバイオマーカーの分析では,インスリン類似成長因子1受容体 (IGF- 1R) と免疫マーカーの活性化が,特にホルモン受容体陽性腫瘍において,ネオアジュバント療法に対する治療反応を予測することが示された.

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