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Updated: Sep 9, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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診断の不確実性から標的治療へ: VEXAS症候群のケースベースレビュー

Gunjan Rana1, Garima Singh2, Mansi Mehta3

  • 1Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA. ranagunjanrana@gmail.com.

Rheumatology international
|September 4, 2025
PubMed
まとめ

VEXAS症候群は,体内のUBA1変異疾患で,重度の炎症と血液の問題があります. IL-1とIL-6を標的とした生物学的治療は,症状の管理とステロイド依存症の軽減に有望である.

キーワード:
自己炎症性疾患生物学的治療グルココルチコイド変異ソマティック幹細胞移植ウビキチン活性化酵素

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