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Updated: Sep 9, 2025

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リトラクション 注: miR-429の過剰発現は,オクラジンの発現を低下させることで,糖尿病マウスの腸内バリア機能を損なう

Tao Yu1, Xi-Ji Lu1, Jie-Yao Li1

  • 1Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yan Jiang Xi Road, Guangzhou, Guangdong, 510120, People's Republic of China.

Cell and tissue research
|September 4, 2025
PubMed
まとめ

No abstract available in PubMed .

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Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
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