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Updated: May 5, 2026

Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease
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Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease

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ミュラー・グリアと網膜のピグメント上皮の間の双方向性低酸素細胞外膀信号は網膜の代謝とバリア機能を調節する

Alaa M Mansour1,2,3, Mohamed S Gad1,2,4, Samar Habib1,2,5

  • 1Department of Oral Biology, The Dental College of Georgia, Augusta University, Augusta, GA 30912, USA.

Biology
|September 4, 2025
PubMed
まとめ

細胞外膀 (EV) は,低酸素状態で網膜の色素上皮 (RPE) とミュラー細胞間の通信を介し,細胞の代謝と機能を変化させます. このEVのクロスストークをターゲットにすることで,不全性網膜症の治療の可能性が生まれます.

キーワード:
ECIS についてGFAP についてミュラー・グリア血網膜障壁エクソソーム細胞外膀低酸素プロテオミクス網膜のピグメント上皮レチノパシー

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