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CAR-T細胞を使って 固体腫瘍の免疫抑制を克服できるのか?

Julia Gwadera1, Maksymilian Grajewski1, Hanna Chowaniec2

  • 1Faculty of Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.

Biology
|September 4, 2025
PubMed
まとめ

エンジニアリングされたキメリック抗原受容体 (CAR) -T細胞は,固体腫瘍の課題を克服する見込みを示しています. 代謝再プログラムや組み合わせ治療のような戦略は,免疫抑制性腫瘍の微小環境に対するCAR-T細胞の有効性を高めることを目的としています.

キーワード:
CAR-T細胞についてCAR-T細胞療法免疫抑制剤固体腫瘍腫瘍の微小環境

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