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Updated: Sep 9, 2025

Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia
07:18

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タオパシーにおける先天性および適応性免疫の新たな役割

Alexis M Johnson1, John R Lukens1

  • 1Center for Brain Immunology and Glia (BIG), Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA 22908, USA; Brain Immunology and Glia Graduate Training Program, University of Virginia, Charlottesville, VA 22908, USA; Harrison Family Translational Research Center in Alzheimer's and Neurodegenerative Diseases, University of Virginia, Charlottesville, VA 22903, USA.

Cell reports
|September 4, 2025
PubMed
まとめ

神経炎症は先天性および適応性免疫によって引き起こされ,タオパシーの進行に大きな影響を及ぼします. 免疫系の反応を活用することで 認知症の治療戦略が生まれます

キーワード:
アルツハイマー病CP: 免疫学CP: 神経科学T細胞適応免疫病気に関連したマイクログリアフロントテンポラル認知症生まれつきの免疫マイクログリア神経変性疾患神経免疫学タオパシー

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