クロモブラストミコシスとフェオヒフォミコシスと関連した入院,米国, 2016-2021
Dallas J Smith1, Kaitlin Benedict1, Shawn R Lockhart1
1Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GeorgiaUnited States of America.
PLoS neglected tropical diseases
|September 4, 2025
まとめ
クロモブラストミコシスとファエオヒフォミコシス,真菌感染症は,米国で重大な入院と死亡を引き起こしました. これらの病原菌の感染を理解することは 公衆衛生戦略にとって極めて重要です
科学分野:
- 感染症
- 菌類学
- 流行病学について
- 公衆衛生
背景:
- クロモブラストミコシスとフェオヒフォミコシスは,脱毛菌によって引き起こされる皮下感染症です.
- 珍しい脳を含むこれらの真菌感染症は,米国では流行病学と結果が十分に理解されていません.
- 効果的な管理のために,国内での入院率と関連するリスク要因に関する正確なデータが必要です.
研究 の 目的:
- 2016年から2021年にかけての米国におけるクロモブラストミコシスおよびフェオヒフォミコシスによる入院率を推定する.
- これらの入院に関連した人口,地域,および臨床的要因を分析する.
- 死亡率や合併症を含む一般的な併発症や入院結果を特定する.
主な方法:
- 医療コストと利用プロジェクト (NIS) の国立入院患者サンプルから得られたデータを使用した.
- クロモブラストミコシスとフェオヒフォミコシス疹の入院例の年間全国推定値
- 診断された患者の人口統計,入院時期,臨床表現,並行した健康状態.
主要な成果:
- 2016年から2021年の間に推定690件の入院が発生し,その割合は2016年にピークに達し,2020年までに減少した.
- 男性,高齢者 (≥65歳),北東地域では入院率が高かった.
- 併発性疾患には高血圧,糖尿病,不血脂症,慢性腎疾患が含まれ,患者の3%が入院中に死亡しました.
結論:
- クロモブラストミコシスとフェオヒフォミコシスは,病院での死亡率とリンパ腫のような合併症と関連しています.
- この研究は,これらの真菌感染症とその関連リスク要因のモニタリングのための重要なベースラインを提供します.
- 病原菌性菌類疾患の理解と管理を改善するために,強化された監視,登録,公衆衛生の意識を推奨しています.
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